PK 11195, an antagonist of peripheral benzodiazepine receptors, reduces ventricular arrhythmias during myocardial ischemia and reperfusion in the dog

Novel dihydropyridines with positive inotropic action through activation of Ca2+ channels

Matthias Schramm, G. Thomas, R. Towart et al. · Nature · 1983 · 1K citations

Life Sciences, Biophysics, Pharmacology +15

Total ischemia in dog hearts, in vitro. 1. Comparison of high energy phosphate production, utilization, and depletion, and of adenine nucleotide catabolism in total ischemia in vitro vs. severe ischemia in vivo.

Robert B. Jennings, K A Reimer, M L Hill et al. · Circulation Research · 1981 · 272 citations · Full text

Life Sciences, Biochemistry, Physiology +16

Differentiation between two ligands for peripheral benzodiazepine binding sites, [3H]R05-4864 and [3H]PK 11195, by thermodynamic studies

G. Le Fur, Nadine Vaucher, M.L. Perrier et al. · Life Sciences · 1983 · 264 citations

Medicine, Medicinal Chemistry, Pharmacology +14

Electrophysiological and pharmacological evidence that peripheral type benzodiazepine receptors are coupled to calcium channels in the heart

M Mestre, Thierry Carriot, Cathérine Belin et al. · Life Sciences · 1985 · 138 citations

Medicine, Pharmacology, Physiology +14

Electrophysiological and pharmacological characterization of peripheral benzodiazepine receptors in a guinea pig heart preparation

M Mestre, Thierry Carriot, Cathérine Belin et al. · Life Sciences · 1984 · 120 citations

Medicine, Cardiology, Pharmacology +13