Concepedia

Acute and multiple-dose studies to determine the safety, tolerability, and pharmacokinetic profile of advantame in healthy volunteers

Steve Warrington, C. Lee, Akira Otabe, Tomoyo Narita, O. Polnjak, Valdis Pīrāgs, Dainis Krieviņš

Food and Chemical Toxicology · 2011 · 19 citations · 1 references

Concepts

PharmacyPharmacokineticsPharmacologyBioavailabilityClinical PharmacologyPharmacodynamicsAdverse Drug Reaction DetectionDrug Safety MonitoringMultiple-dose Peak Time

References

1

Pharmacokinetics and metabolism of N-[N-[3-(3-hydroxy-4-methoxyphenyl) propyl]-α-aspartyl]-l-phenylalanine 1-methyl ester, monohydrate (advantame) in the rat, dog, and man

Kazuyuki Ubukata, Akira Nakayama, Ryuichi Mihara · Food and Chemical Toxicology · 2011 · 15 citations

Medicine, Pharmacokinetics, Pharmacology +6