Concepedia

Multiple-dose Peak Time

Multiple-Dose Peak Time is a pharmacokinetic metric that denotes the time at which the maximum plasma concentration is achieved following the administration of multiple doses of a drug, distinguishing it from single-dose peak time by accounting for accumulation and steady-state pharmacokinetics.

8

Publications

365

Citations

47

Authors

21

Institutions

Publications per year

2017–2026

0

Variants

Multiple-dose Tmax

Parents

Publications

8

Pharmacokinetic Properties of Mirabegron, a β3-Adrenoceptor Agonist: Results From Two Phase I, Randomized, Multiple-Dose Studies in Healthy Young and Elderly Men and Women

Walter Krauwinkel, Jan van Dijk, Marloes Schaddelee et al. · Clinical Therapeutics · 2012 · 96 citations

, , +7

Accumulation Pharmacokinetics of Tobramycin

Jerome J. Schentag, George Lasezkay, Thomas J. Cumbo et al. · Antimicrobial Agents and Chemotherapy · 1978 · 67 citations · Full text

, , +17

Pharmacokinetics, Pharmacodynamics and Safety of Tolvaptan, A Novel, Oral, Selective Nonpeptide AVP V2-receptor Antagonist: Results of Single- and Multiple-Dose Studies in Healthy Japanese Male Volunteers

Seong Ryul Kim, Tomoko Hasunuma, Osamu Satō et al. · Cardiovascular Drugs and Therapy · 2011 · 54 citations

, , +6

Single- and multiple-dose kinetics of oral lorazepam in humans: The predictability of accumulation

David J. Greenblatt, Marcia D. Allen, Dean S. MacLaughlin et al. · Journal of Pharmacokinetics and Biopharmaceutics · 1979 · 42 citations

, , +13

Single- and multiple-dose kinetics of estazolam, a triazolo benzodiazepine

Marcia D. Allen, David J. Greenblatt, John D. Arnold · Psychopharmacology · 1979 · 36 citations

, , +12

1–5 of 8

Authors

47

  1. DJ
    David J. Greenblatt

    Tufts University, United States

    2 publications · 78 citations

    2

    h-index

  2. MD
    Marcia D. Allen

    Massachusetts General Hospital, United States

    2 publications · 78 citations

    2

    h-index

  3. OS
    Osamu Satō

    University of Massachusetts Chan Medical School, United States

    1 publications · 54 citations

    1

    h-index

  4. DH
    David H. Huffman

    University of Kansas Medical Center, United States

    1 publications · 42 citations

    1

    h-index

  5. GS
    Grégory Strabach

    Astellas Pharma (Netherlands), Netherlands

    1 publications · 96 citations

    1

    h-index

1–5 of 47

Institutions

21

  1. Massachusetts General Hospital

    Boston, United States

    2 h-index

    4 publications

    156 citations

  2. Otsuka (Japan)

    Tokyo, Japan

    1 h-index

    4 publications

    216 citations

  3. Massachusetts Mental Health Center

    Boston, United States

    1 h-index

    2 publications

    84 citations

  4. Pauls Stradiņš Clinical University Hospital

    Riga, Latvia

    1 h-index

    3 publications

    57 citations

  5. University at Buffalo, State University of New York

    Buffalo, United States

    1 h-index

    5 publications

    335 citations

  6. Hammersmith Medicines Research

    London, United Kingdom

    1 h-index

    1 publications

    19 citations

  7. Astellas Pharma (Netherlands)

    Leiden, Netherlands

    1 h-index

    6 publications

    576 citations

  8. Kitasato Institute Hospital

    Tokyo, Japan

    1 h-index

    1 publications

    54 citations

1–8 of 21

Venues

  1. Food and Chemical Toxicology

    1 publications · 19 citations

    1

    h-index

  2. Antimicrobial Agents and Chemotherapy

    AAC · 1 publications · 67 citations

    1

    h-index

  3. Inflammation Research

    IR · 1 publications · 16 citations

    1

    h-index

  4. The Journal of Clinical Pharmacology

    1 publications · 35 citations

    1

    h-index

  5. 1

    h-index

1–5