Cytochrome P450 2C8 and CYP3A4/5 are involved in chloroquine metabolism in human liver microsomes

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

Tsutomu Shimada, Hiroshi Yamazaki, Mayumi Mimura et al. · Journal of Pharmacology and Experimental Therapeutics · 1994 · 2.8K citations

Medicine, Biochemistry, Pharmacology +15

Cytochrome P450 isoform inhibitors as a tool for the investigation of metabolic reactions catalyzed by human liver microsomes.

Martine Bourrié, Viviane Meunier, Yves Berger et al. · Journal of Pharmacology and Experimental Therapeutics · 1996 · 362 citations

Medicine, Biochemistry, Pharmacology +15

Use of midazolam as a human cytochrome P450 3A probe: I. In vitro-in vivo correlations in liver transplant patients.

Kenneth E. Thummel, Danny D. Shen, Terry Podoll et al. · Journal of Pharmacology and Experimental Therapeutics · 1994 · 356 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes

Victoria A. Eagling, John Tjia, David Back · British Journal of Clinical Pharmacology · 1998 · 336 citations · Full text

Medicine, Pharmacology, Biochemical Pharmacology +14

Specificity of substrate and inhibitor probes for human cytochromes P450 1A1 and 1A2.

Wichittra Tassaneeyakul, Donald Birkett, M Veronese et al. · Journal of Pharmacology and Experimental Therapeutics · 1993 · 317 citations

Medicine, Biochemistry, Pharmacology +17