Concepedia

Early Neutrophilia Is Associated With Volume of Ischemic Tissue in Acute Stroke

Brian Buck, David S. Liebeskind, Jeffrey L. Saver, Oh Young Bang, Susan W. Yun, Sidney Starkman, Latisha K. Ali, Doojin Kim, J. Pablo Villablanca, Noriko Salamon,

Stroke · 2007 · 307 citations · 22 references

DOI

Abstract

Higher peripheral leukocyte and neutrophil counts, but not lymphocyte counts, are associated with larger infarct volumes in acute ischemic stroke. Attenuating neutrophilic response early after ischemic stroke may be a viable therapeutic strategy and warrants further study.

References

22

Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment.

Harold P. Adams, Birgitte H. Bendixen, L. Jaap Kappelle et al. · Stroke · 1993 · 12K citations · Full text

Quantile Regression

Roger Koenker, Kevin F. Hallock · The Journal of Economic Perspectives · 2001 · 4.2K citations

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Peak plasma interleukin-6 and other peripheral markers of inflammation in the first week of ischaemic stroke correlate with brain infarct volume, stroke severity and long-term outcome

Craig J. Smith, Hedley Emsley, C Gavin et al. · BMC Neurology · 2004 · 483 citations · Full text

Acute Stroke Therapy by Inhibition of Neutrophils (ASTIN)

Michael Krams, Kennedy R. Lees, Werner Hacke et al. · Stroke · 2003 · 425 citations

Gene Expression in Blood Changes Rapidly in Neutrophils and Monocytes after Ischemic Stroke in Humans: A Microarray Study

Yang Tang, Huichun Xu, Xin Du et al. · Journal of Cerebral Blood Flow & Metabolism · 2006 · 325 citations · Full text