Cholesterol Potentiates ABCG2 Activity in a Heterologous Expression System: Improved in Vitro Model to Study Function of Human ABCG2

ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins

Nan Wang, Debin Lan, Wengen Chen et al. · Proceedings of the National Academy of Sciences · 2004 · 1.1K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Disruption of <i>Abcg5</i> and <i>Abcg8</i> in mice reveals their crucial role in biliary cholesterol secretion

Liqing Yu, Robert E. Hammer, Jia Li-Hawkins et al. · Proceedings of the National Academy of Sciences · 2002 · 715 citations

Life Sciences, Biochemistry, Molecular Biology +17

Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C.

Arnold van Loevezijn, Jeany M Lakhai, Martin van der Valk et al. · PubMed · 2002 · 687 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Role of Breast Cancer Resistance Protein in the Bioavailability and Fetal Penetration of Topotecan

Johan W. Jonker · JNCI Journal of the National Cancer Institute · 2000 · 639 citations · Full text

Medicine, Oncology, Pharmacology +17

Expression of the human multidrug resistance cDNA in insect cells generates a high activity drug-stimulated membrane ATPase.

Balázs Sarkadi, Elmer M. Price, R. C. Boucher et al. · Journal of Biological Chemistry · 1992 · 632 citations · Full text

Medicine, Cell Biology, Cellular Pharmacology +7