Gliotoxin promotes Aspergillus fumigatus internalization into type II human pneumocyte A549 cells by inducing host phospholipase D activation

Aspergillus fumigatus Triggers Inflammatory Responses by Stage-Specific β-Glucan Display

Tobias M. Hohl, Heather L. Van Epps, Amariliz Rivera et al. · PLoS Pathogens · 2005 · 430 citations · Full text

Inflammation, Fungal Cell Biology, Innate Immune Receptor +12

The immunosuppressive fungal metabolite gliotoxin specifically inhibits transcription factor NF-kappaB.

Heike L. Pahl, B Krauss, Klaus Schulze‐Osthoff et al. · The Journal of Experimental Medicine · 1996 · 335 citations · Full text

Inflammation, Cytokine, Dna Binding +15

Gliotoxin Is a Virulence Factor of <i>Aspergillus fumigatus</i> : <i>gliP</i> Deletion Attenuates Virulence in Mice Immunosuppressed with Hydrocortisone

Janyce A. Sugui, Julián Pardo, Yun C. Chang et al. · Eukaryotic Cell · 2007 · 238 citations · Full text

Microbial Toxin, Mutant Strain, Health Sciences +15

Purification and characterization of factors produced by Aspergillus fumigatus which affect human ciliated respiratory epithelium

Ryoichi Amitani, Graham W. Taylor, E N Elezis et al. · Infection and Immunity · 1995 · 199 citations · Full text

Aspergillus fumigatus suppresses the human cellular immune response via gliotoxin-mediated apoptosis of monocytes

Marta Stanzani, Enrico Orciuolo, Russell E. Lewis et al. · Blood · 2004 · 199 citations