Frequency and parental origin of hypermethylated RB1 alleles in retinoblastoma

Analysis of human Y-chromosome-specific reiterated DNA in chromosome variants.

Louis M. Kunkel, Kirby D. Smith, Samuel H. Boyer et al. · Proceedings of the National Academy of Sciences · 1977 · 1.4K citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma

Valerie Greger, Eberhard Passarge, Wolfgang H�pping et al. · Human Genetics · 1989 · 566 citations

Medicine, Molecular Biology, Oncology +14

Allele-specific hypermethylation of the retinoblastoma tumor-suppressor gene.

Toshiyuki Sakai, Junya Toguchida, Naoko Ohtani et al. · PubMed · 1991 · 475 citations

Life Sciences, Genetics, Molecular Genetics +14

CpG methylation inactivates the promoter activity of the human retinoblastoma tumor-suppressor gene.

Naoko Ohtani‐Fujita, Tsuyoshi Fujita, Akira Aoike et al. · PubMed · 1993 · 317 citations

Medicine, Genetics, Molecular Genetics +16

Prediction of the Risk of Hereditary Retinoblastoma, Using DNA Polymorphisms within the Retinoblastoma Gene

Janey L. Wiggs, Magnus Nordenskjöld, David W. Yandell et al. · New England Journal of Medicine · 1988 · 243 citations

Life Sciences, Genetics, Molecular Genetics +17