Insights into the Biosynthesis of Hormaomycin, An Exceptionally Complex Bacterial Signaling Metabolite

The specificity-conferring code of adenylation domains in nonribosomal peptide synthetases

Torsten Stachelhaus, Henning D. Mootz, Mohamed A. Marahiel · Chemistry & Biology · 1999 · 1.2K citations · Full text

Biosynthesis, Nonribosomal Peptide Synthetases, Biochemistry +10

Construction of T-vectors, a rapid and general system for direct cloning of unmodified PCR products

Douglas A. Marchuk, Mitchell L. Drumm, Ann M. Saulino et al. · Nucleic Acids Research · 1991 · 1.2K citations · Full text

Unmodified Pcr Products, Engineering, Direct Cloning +13

Predictive, structure-based model of amino acid recognition by nonribosomal peptide synthetase adenylation domains

Gregory L. Challis, Jacques Ravel, Craig A. Townsend · Chemistry & Biology · 2000 · 805 citations · Full text

Biochemistry, Biomolecular Structure Prediction, Protein Folding +12

Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S

Elena Conti · The EMBO Journal · 1997 · 721 citations · Full text

Non-ribosomal Biosynthesis, Biosynthesis, Biotransformation +9

Advances in Enzymology

Traci Mann · Nature · 1963 · 595 citations

Biosynthesis, Engineering, Cellular Enzymology +5