Ketoconazole inhibits the biosynthesis of leukotrienes in vitro and in vivo

Leukotrienes: Mediators of Immediate Hypersensitivity Reactions and Inflammation

Bengt Samuelsson · Science · 1983 · 2.9K citations

Life Sciences, Immunology, Pharmacology +14

Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes

A. W. Ford‐Hutchinson, M.A. Bray, Mira Doig et al. · Nature · 1980 · 2.1K citations

Life Sciences, Cell Biology, Pharmacology +12

The human PMN leukocyte chemotactic activity of complex hydroxy-eicosatetraenoic acids (HETEs).

E J Goetzl, W C Pickett · The Journal of Immunology · 1980 · 516 citations

Life Sciences, Biochemistry, Immunology +12

A new approach to anti-inflammatory drugs

G.A. Higgs, Roderick J. Flower, John R. Vane · Biochemical Pharmacology · 1979 · 503 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Inhibition of leukotriene biosynthesis by the leukocyte product 15-hydroxy-5,8,11,13-eicosatetraenoic acid.

Jack Y. Vanderhoek, Robert W. Bryant, Jennifer M. Bailey · Journal of Biological Chemistry · 1980 · 326 citations · Full text

Life Sciences, Biochemistry, Pharmacology +13