Are Transglutaminase 2 Inhibitors Able to Reduce Gliadin-Induced Toxicity Related to Celiac Disease? A Proof-of-Concept Study

Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease

Øyvind Molberg, Stephen N. McAdam, Roman Körner et al. · Nature Medicine · 1998 · 1.2K citations

Inflammation, Autoimmune Disease, Mucosal Immunology +11

Association between innate response to gliadin and activation of pathogenic T cells in coeliac disease

Luigi Maiuri, Carolina Ciacci, Ida Ricciardelli et al. · The Lancet · 2003 · 610 citations

Host Response, Allergy, Autoimmune Disease +12

Tissue transglutaminase autoantibody enzyme-linked immunosorbent assay in detecting celiac disease

Satu Sulkanen, T. Halttunen, Kaija Laurila et al. · Gastroenterology · 1998 · 607 citations · Full text

Food Intolerance, Autoimmune Disease, Celiac Disease +10

Gliadin Induces an Increase in Intestinal Permeability and Zonulin Release by Binding to the Chemokine Receptor CXCR3

Karen M. Lammers, Ruliang Lu, Julie Brownley et al. · Gastroenterology · 2008 · 527 citations · Full text

Inflammation, Intestinal Permeability, Zonulin Release +12

Organ culture of mucosal biopsies of human small intestine

Thomas H. Browning, Jerry S. Trier · Journal of Clinical Investigation · 1969 · 360 citations · Full text

Immunology, Gastroenterology, Pathology +17