Point Mutations and Deletion Responsible for the <i>Bombay</i> H null and the <i>Reunion</i> H weak Blood Groups

Abstract

Single prevalent FUT1 and FUT2 point mutations and a deletion are responsible for the Indian Bombay H null and the Reunion H weak phenotypes found on Reunion island. This is in contrast with other H-deficient phenotypes where sporadic nonprevalent inactivating mutations are the rule.