Sazetidine-A, a Selective α4β2 Nicotinic Receptor Desensitizing Agent and Partial Agonist, Reduces Nicotine Self-Administration in Rats

Efficacy of Varenicline, an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist, vs Placebo or Sustained-Release Bupropion for Smoking Cessation<SUBTITLE>A Randomized Controlled Trial</SUBTITLE>

Douglas E. Jorenby · JAMA · 2006 · 1.7K citations

Medicine, Pharmacology, Pharmacotherapy +17

A study of the ‘desensitization’ produced by acetylcholine at the motor end‐plate

B. Katz, S. Thesleff · The Journal of Physiology · 1957 · 1.5K citations

Medicine, Neurobiology, Neuroscience +14

Nicotine maintains robust self-administration in rats on a limited-access schedule

William A. Corrigall, Kathleen M. Coen · Psychopharmacology · 1989 · 589 citations

Medicine, Behavioral Sciences, Pharmacology +14

Pharmacological profile of the α4β2 nicotinic acetylcholine receptor partial agonist varenicline, an effective smoking cessation aid

Hans Rollema, Leslie K. Chambers, J.W. Coe et al. · Neuropharmacology · 2006 · 535 citations

Public Health, Pharmacology, Pharmacotherapy +14

Nicotine self-administration in rats: strain and nicotine pre-exposure effects on acquisition

M. Shoaib, Charles W. Schindler, Steven R. Goldberg · Psychopharmacology · 1997 · 235 citations

Medicine, Behavioral Sciences, Pharmacology +13