<i>Trichomonas vaginalis</i>Infection Induces Vaginal CD4⁺T-Cell Infiltration in a Mouse Model: A Vaccine Strategy to Reduce Vaginal Infection and HIV Transmission

Abstract

The vaccine induces local and systemic immune responses and confers significantly greater protection against vaginal infection than seen in unvaccinated mice (P < .005). These data support the potential for a human vaccine against T. vaginalis infection that could also influence the incidence of human immunodeficiency virus infection.