Concepedia

Towards a combined prognostic index for survival in HIV infection: the role of ‘non‐HIV’ biomarkers

KA McGinnis, Melissa Skanderson, CL Gibert, David Rimland, MC Rodriguez‐Barradas, KK Oursler, ST Brown, R. Scott Braithwaite, Margaret May, KE Covinsky,

HIV Medicine · 2009 · 156 citations · 42 references

DOIFull text

Open access

Abstract

When added to HIV biomarkers, 'non-HIV' biomarkers improve differentiation of mortality. When evaluated over similar intervals, the VACS Index discriminates as well as other established indices. After further validation, the VACS Index may provide a useful, integrated risk assessment for management and research.

References

42

A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation

Mary E. Charlson, Peter Pompei, Kathy L. Aleš et al. · Journal of Chronic Diseases · 1987 · 48.8K citations

, , +11

Development of a simple noninvasive index to predict significant fibrosis in patients with HIV/HCV coinfection†‡

Richard K. Sterling, Eduardo Lissen, Nathan Clumeck et al. · Hepatology · 2006 · 4.6K citations · Full text

Assessing Kidney Function — Measured and Estimated Glomerular Filtration Rate

Lesley A. Stevens, Josef Coresh, Tom Greene et al. · New England Journal of Medicine · 2006 · 2.9K citations

, , +13

CD4+ Count–Guided Interruption of Antiretroviral Treatment

New England Journal of Medicine · 2006 · 2.2K citations · Full text

APACHE—acute physiology and chronic health evaluation: a physiologically based classification system

William A. Knaus, Jack E. Zimmerman, Douglas P. Wagner et al. · Critical Care Medicine · 1981 · 2.2K citations

, , +19