A novel DNA polymerase in the hyperthermophilic archaeon, <i>Pyrococcus furiosus</i>: gene cloning, expression, and characterization

Abstract

In P. furiosus, we identified a second DNA polymerase encoded by two genes, neither of which display significant homology to any other known DNA polymerase. Both the enzymatic properties of the enzyme and the gene organization raise the possibility that this enzyme might be the replicative DNA polymerase of P. furiosus.