Concepedia

Down-Regulation of Yes Associated Protein 1 Expression Reduces Cell Proliferation and Clonogenicity of Pancreatic Cancer Cells

Caroline H. Diep, Kelly Zucker, Galen Hostetter, Aprill Watanabe, Chengcheng Hu, Rubén M. Muñoz, Daniel D. Von Hoff, Haiyong Han

PLoS ONE · 2012 · 85 citations · 39 references

DOIFull text

Open access

Abstract

YAP1 is overexpressed in pancreatic cancer tissues and potentially plays an important role in the clonogenicity and growth of pancreatic cancer cells.

References

39

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 176.9K citations

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Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

Bin Zhao, Xiaomu Wei, Weiquan Li et al. · Genes & Development · 2007 · 3.1K citations · Full text

Elucidation of a Universal Size-Control Mechanism in Drosophila and Mammals

Jixin Dong, Georg Feldmann, Jianbin Huang et al. · Cell · 2007 · 2.4K citations · Full text

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The Hippo–YAP pathway in organ size control and tumorigenesis: an updated version

Bin Zhao, Li Li, Qun‐Ying Lei et al. · Genes & Development · 2010 · 1.1K citations · Full text

Identification and Validation of Oncogenes in Liver Cancer Using an Integrative Oncogenomic Approach

Lars Zender, Mona S. Spector, Wen Xue et al. · Cell · 2006 · 1.1K citations · Full text

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