A new enantioselective synthesis of glycidates via dynamic kinetic resolution of racemic 2-chloro-3-keto esters using chiral Ru (II) complexes

First total synthesis of taxol. 1. Functionalization of the B ring

Robert A. Holton, Carmen Somoza, Hyeong Baik Kim et al. · Journal of the American Chemical Society · 1994 · 629 citations

Natural Sciences, Chemistry, Medicinal Chemistry +11

First total synthesis of taxol. 2. Completion of the C and D rings

Robert A. Holton, Hyeong Baik Kim, Carmen Somoza et al. · Journal of the American Chemical Society · 1994 · 524 citations

Natural Sciences, Chemistry, Analytical Chemistry +8

Stereoselective hydrogenation via dynamic kinetic resolution

Ryōji Noyori, Tomohiko Ikeda, Takeshi Ohkuma et al. · Journal of the American Chemical Society · 1989 · 444 citations

Natural Sciences, Chemistry, Catalysis +7

Taxol and taxotere: discovery, chemistry, and structure-activity relationships

Daniel Guénard, Françoise Guéritte-Voegelein, Pierre Potìer · Accounts of Chemical Research · 1993 · 442 citations

Pharmacy, Chemistry, Pharmacology +10

A practical, highly enantioselective synthesis of the taxol side chain via asymmetric catalysis.

Li Deng, Eric N. Jacobsen · The Journal of Organic Chemistry · 1992 · 300 citations

Natural Sciences, Chemistry, Biocatalysis +10