IGFBP-3 hypermethylation-derived deficiency mediates cisplatin resistance in non-small-cell lung cancer

Cancer Statistics, 2008

Ahmedin Jemal, Rebecca L. Siegel, Elizabeth Ward et al. · CA A Cancer Journal for Clinicians · 2008 · 10.2K citations · Full text

Cancer Statistics, Epidemiology, Cancer Epidemiology +14

5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

Adrian Merlo, James G. Herman, Li Mao et al. · Nature Medicine · 1995 · 2K citations

Tumor Biology, Transcriptional Regulation, Medicine +14

Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

Stephen B. Baylln, James G. Herman, Jeremy R. Graff et al. · Advances in cancer research · 1997 · 1.9K citations

Chromatin, Epigenetic Change, Genetics +5

Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia.

Manel Esteller, Stanley R. Hamilton, P C Burger et al. · PubMed · 1999 · 1.3K citations

Common Event, Epigenetic Change, Genetics +16

Induction of the growth inhibitor IGF-binding protein 3 by p53

Leonard Buckbinder, Randy Talbott, Susana Velasco-Miguel et al. · Nature · 1995 · 877 citations

Cell Proliferation, Cell Biology, Cell Growth +7