Consumption of redox energy by glutathione metabolism contributes to hypoxia/ reoxygenation-induced injury in astrocytes

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues

Frank Tietze · Analytical Biochemistry · 1969 · 6.1K citations

Life Sciences, Biochemistry, Analytical Chemistry +14

Characterization of the Cellular Reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT): Subcellular Localization, Substrate Dependence, and Involvement of Mitochondrial Electron Transport in MTT Reduction

Michael V. Berridge, An S. Tan · Archives of Biochemistry and Biophysics · 1993 · 1.4K citations

Life Sciences, Biochemistry, Cell Biology +15

Glutathione is present in high concentrations in cultured astrocytes but not in cultured neurons

Stephen P. Raps, James C. K. Lai, Leif Hertz et al. · Brain Research · 1989 · 418 citations

Life Sciences, Neurobiology, Neuroscience +13

Vitamin E, Ascorbate, Glutathione, Glutathicne Disulfide, and Enzymes of Glutathione Metabolism in Cultures of Chick Astrocytes and Neurons: Evidence that Astrocytes Play an Important Role in Antioxidative Processes in the Brain

Tapas K. Makar, Maiken Nedergaard, Axel Preuss et al. · Journal of Neurochemistry · 1994 · 416 citations

Life Sciences, Biochemistry, Neuroscience +16

Antioxidant defense of the brain: a role for astrocytes

John X. Wilson · Canadian Journal of Physiology and Pharmacology · 1997 · 404 citations

Life Sciences, Neurobiology, Neuroscience +17