Synthesis of anthracyclinones by electrophilic and nucleophilic addition to anthraquinones

Bioactivation as a Model for Drug Design Bioreductive Alkylation

Harold W. Moore · Science · 1977 · 433 citations

Medicine, Pharmacology, Drug Design +5

(α-Alkylation of α-heterosubstituted carboxylic acids without racemization

Dieter Seebàch, Reto Naef, Giorgio Calderari · Tetrahedron · 1984 · 285 citations

Natural Sciences, Chemistry, Medicinal Chemistry +10

The Chemistry of Carbenoids and Other Thermolabile Organolithium Compounds

Gert Köbrich · Angewandte Chemie International Edition in English · 1972 · 224 citations

Natural Sciences, Chemistry, Inorganic Chemistry +7

Frontier molecular orbital theory of substitutent effects on regioselectivities of nucleophilic additions and cycloadditions to benzoquinones and naphthoquinones

Melvin D. Rozeboom, Inga Mai Tegmo-Larsson, K. N. Houk · The Journal of Organic Chemistry · 1981 · 140 citations

Natural Sciences, Chemistry, Computational Chemistry +8

One-step procedure for the preparation of tertiary .alpha.-ketols from the corresponding ketones

John N. Gardner, F. E. Carlon, O. Gnoj · The Journal of Organic Chemistry · 1968 · 129 citations

Natural Sciences, Biochemistry, Chemistry +7