Concepedia

Synthesis and biological evaluation of sulfonylhydrazone-substituted imidazo[1,2-a]pyridines as novel PI3 kinase p110α inhibitors

Masahiko Hayakawa, Kenichi Kawaguchi, Hiroyuki Kaizawa, Tomonobu Koizumi, Takahide Ohishi, Mayumi Yamano, Minoru Okada, Mitsuaki Ohta, Shin‐ichi Tsukamoto, Florence I. Raynaud,

Bioorganic & Medicinal Chemistry · 2007 · 121 citations · 12 references

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12

High Frequency of Mutations of the <i>PIK3CA</i> Gene in Human Cancers

Yardena Samuels, Zhenghe Wang, Alberto Bardelli et al. · Science · 2004 · 3.4K citations

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PIK3CA is implicated as an oncogene in ovarian cancer

Laleh Shayesteh, Yiling Lu, Wen-Lin Kuo et al. · Nature Genetics · 1999 · 1.2K citations

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A Pharmacological Map of the PI3-K Family Defines a Role for p110α in Insulin Signaling

Zachary A. Knight, Beatriz González, Morri E. Feldman et al. · Cell · 2006 · 1.2K citations · Full text

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Mutation of the <b> <i>PIK3CA</i> </b> Gene in Ovarian and Breast Cancer

Ian Campbell, Sarah E. Russell, David Y.H. Choong et al. · Cancer Research · 2004 · 914 citations · Full text

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Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic

Sohye Kang, Andreas G. Bader, Peter K. Vogt · Proceedings of the National Academy of Sciences · 2005 · 824 citations · Full text

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