Concepedia

Catalytic, enantio- and diastereoselective synthesis of γ-butyrolactones incorporating quaternary stereocentres

Francesco Manoni, Claudio Cornaggia, James I. Murray, Seán Tallon, Stephen J. Connon

Chemical Communications · 2012 · 49 citations · 32 references

DOI

Concepts

Abstract

A new, highly enantio- and diastereoselective catalytic asymmetric formal cycloaddition of aryl succinic anhydrides and aldehydes which generates paraconic acid (γ-butyrolactone) derivatives is reported.

References

32

Synthesis and Biological Activity of α‐Methylene‐γ‐butyrolactones

H. M. R. Hoffmann, Jürgen P. Rabe · Angewandte Chemie International Edition in English · 1985 · 647 citations

, , +15

Enantioselective Synthesis of Paraconic Acids

Rakeshwar B. Chhor, Bernd Nosse, Sebastian Sörgel et al. · Chemistry - A European Journal · 2002 · 126 citations

, , +13

Condensation of imines with homophthalic anhydrides. A convergent synthesis of cis- and trans-13-methyltetrahydroprotoberberines

Mark Cushman, John Gentry, Frederick W. Dekow · The Journal of Organic Chemistry · 1977 · 119 citations

, , +6

Condensation of succinic anhydride with N-benzylidene-N-methylamine. Stereoselective synthesis of trans- and cis-1-methyl-4-carboxy-5-phenyl-2-pyrrolidinone

Neal Castagnoli · The Journal of Organic Chemistry · 1969 · 107 citations

, , +6

Antimalarial Dihydroisocoumarins Produced by <i>Geotrichum</i> sp., an Endophytic Fungus of <i>Crassocephalum </i><i>c</i><i>repidioides</i>

Palangpon Kongsaeree, Samran Prabpai, Nongluksna Sriubolmas et al. · Journal of Natural Products · 2003 · 106 citations

, , +17