Tissue specific induction of cytochrome P450 (CYP) 1A1 and 1B1 in rat liver and lung following in vitro (tissue slice) and in vivo exposure to benzo(a)pyrene

IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans

R. L. Carter · Journal of Clinical Pathology · 1980 · 3.5K citations · Full text

Occupational Toxicology, Oncology, Medicine +13

Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1.

Tsutomu Shimada, Carrie L. Hayes, Hiroshi Yamazaki et al. · PubMed · 1996 · 795 citations

Chemoprevention Strategy, Escherichia Coli, Chemical Biology +17

Benzo[ <i>a</i> ]pyrene carcinogenicity is lost in mice lacking the aryl hydrocarbon receptor

Yasuhito Shimizu, Yoko Nakatsuru, Masao Ichinose et al. · Proceedings of the National Academy of Sciences · 2000 · 627 citations

Metabolism of benzo[a]pyrene and benzo[a]pyrene-7,8-diol by human cytochrome P450 1B1

Jiyoung Kim · Carcinogenesis · 1998 · 284 citations · Full text

Metabolomic Profiling, Secondary Metabolite, Organic Chemistry +18

Monoclonal antibodies to liver microsomal cytochrome P-450E of the marine fish Stenotomus chrysops (scup): Cross reactivity with 3-methylcholanthrene induced rat cytochrome P-450

Sang S. Park, Haruko Miller, Alan V. Klotz et al. · Archives of Biochemistry and Biophysics · 1986 · 180 citations

Cross Reactivity, Microsomal Cytochrome P-450e, Biochemistry +14