A survey of artemisinic and dihydroartemisinic acid contents in glasshouse and global field-grown populations of the artemisinin-producing plant Artemisia annua L.

Production of the antimalarial drug precursor artemisinic acid in engineered yeast

Dae‐Kyun Ro, Eric M. Paradise, Mario Ouellet et al. · Nature · 2006 · 2.8K citations

Biosynthesis, Engineering, Biochemistry +6

Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin

Patrick J. Westfall, Douglas J. Pitera, Jacob R. Lenihan et al. · Proceedings of the National Academy of Sciences · 2012 · 711 citations · Full text

Continuous‐Flow Synthesis of the Anti‐Malaria Drug Artemisinin

François Lévesque, Peter H. Seeberger · Angewandte Chemie International Edition · 2012 · 501 citations

Medicinal Chemistry, Continuous‐flow Synthesis, Pharmaceutical Science +14

The Genetic Map of <i>Artemisia annua</i> L. Identifies Loci Affecting Yield of the Antimalarial Drug Artemisinin

Ian A. Graham, Susan Blumer, Caroline Branigan et al. · Science · 2010 · 342 citations

Plant Genetics, Antiparasitic Agent, Genetic Map +22

The Molecular Cloning of Artemisinic Aldehyde Δ11(13) Reductase and Its Role in Glandular Trichome-dependent Biosynthesis of Artemisinin in Artemisia annua

Yansheng Zhang, Keat H. Teoh, Darwin W. Reed et al. · Journal of Biological Chemistry · 2008 · 301 citations · Full text