Tumor necrosis factor-α -308 G>A and interleukin-6 -174 G>C promoter polymorphisms and pemphigus

The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis.

Daniel Fishman, Gary Faulds, Rachel Jeffery et al. · Journal of Clinical Investigation · 1998 · 2.2K citations · Full text

Il-6 Genotype, Immunology, Genetic Epidemiology +24

Cooperative Influence of Genetic Polymorphisms on Interleukin 6 Transcriptional Regulation

Catherine Terry, Valérie Loukaci, Fiona R. Green · Journal of Biological Chemistry · 2000 · 796 citations · Full text

Polymorphic structure of the tumor necrosis factor (TNF) locus: an NcoI polymorphism in the first intron of the human TNF-beta gene correlates with a variant amino acid in position 26 and a reduced level of TNF-beta production.

Gerald Messer, Ulrich Spengler, M. Jung et al. · The Journal of Experimental Medicine · 1991 · 548 citations · Full text

Immunology, Immune Regulation, Cell Death +18

Relevance of the tumor necrosis factor alpha (TNF alpha) -308 promoter polymorphism in TNF alpha gene regulation.

B M Brinkman, D Zuijdeest, Eric L. Kaijzel et al. · PubMed · 1997 · 289 citations

Immunology, Immune Regulation, Cell Death +18

Cytokine gene polymorphisms in patients infected with hepatitis B virus

Ziv Ben‐Ari, Eytan Mor, Orit Papo et al. · The American Journal of Gastroenterology · 2003 · 219 citations