Allele-specific polymerase chain reaction diagnostic test for the functional MDR1 polymorphism in dogs

P-Glycoprotein, a gatekeeper in the blood–brain barrier

Alfred H. Schinkel · Advanced Drug Delivery Reviews · 1999 · 954 citations

Medicine, Neuroscience, Pharmacology +8

Ivermectin sensitivity in collies is associated with a deletion mutation of the mdr1 gene

Katrina L. Mealey, Steve A. Bentjen, John Gay et al. · Pharmacogenetics · 2001 · 452 citations

Medicine, Pharmacology, Veterinary Pharmacology +16

Breed distribution and history of canine <i>mdr1-1Δ</i> , a pharmacogenetic mutation that marks the emergence of breeds from the collie lineage

Mark W. Neff, Kathryn Robertson, Aaron K. Wong et al. · Proceedings of the National Academy of Sciences · 2004 · 199 citations · Full text

Veterinary Medicine, Genetics, Molecular Genetics +15

MDR1-deficient genotype in Collie dogs hypersensitive to the P-glycoprotein substrate ivermectin

Alain Roulet, Olivier Puel, Stéphane Gesta et al. · European Journal of Pharmacology · 2003 · 168 citations

Life Sciences, Veterinary Pharmacology, Hypersensitivity +2

Increased toxicity of P-glycoprotein-substrate chemotherapeutic agents in a dog with the MDR1 deletion mutation associated with ivermectin sensitivity

Katrina L. Mealey, Nicole C. Northrup, Steven A. Bentjen · Journal of the American Veterinary Medical Association · 2003 · 100 citations · Full text

Medicine, Pharmacology, Veterinary Pharmacology +13