The anesthetics nitrous oxide and ketamine are more neurotoxic to old than to young rat brain

Glutamate Receptor Dysfunction and Schizophrenia

John W. Olney · Archives of General Psychiatry · 1995 · 1.7K citations

Medicine, Neuroscience, Psychiatry +17

Pathological Changes Induced in Cerebrocortical Neurons by Phencyclidine and Related Drugs

John W. Olney, Joann Labruyere, Madelon T. Price · Science · 1989 · 1.3K citations

Medicine, Neuroscience, Pharmacology +17

NMDA Antagonist Neurotoxicity: Mechanism and Prevention

John W. Olney, Joann Labruyere, G. Wang et al. · Science · 1991 · 850 citations

Medicine, Neuroscience, Pharmacology +17

Blocking of acquisition but not expression of conditioned fear-potentiated startle by NMDA antagonists in the amygdala

Mindy J.D. Miserendino, Catherine B. Sananes, Kathleen R. Melia et al. · Nature · 1990 · 821 citations

Life Sciences, Neurobiology, Neuroscience +13

Oxidative damage to mitochondrial DNA shows marked age‐dependent increases in human brain

Patrizia Mecocci, Usha MacGarvey, A. Kaufman et al. · Annals of Neurology · 1993 · 757 citations

Life Sciences, Genetics, Neuroscience +15