Concepedia

Ketamine Toxicity

Ketamine Toxicity is a pharmacological phenomenon characterized by adverse physiological and psychological effects resulting from the excessive or prolonged exposure to ketamine, a dissociative anesthetic and NMDA receptor antagonist, distinguishing it from other hallucinogen toxicities by its unique mechanism of glutamatergic dysregulation and associated neurotoxic, urotoxic, and psychotomimetic outcomes.

321

Publications

17.7K

Citations

1.5K

Authors

534

Institutions

Publications per year

2017–2026

99

Parents

Publications

321

Ketamine—Its Pharmacology and Therapeutic Uses

Paul F. White, Walter L. Way, Anthony J. Trevor · Anesthesiology · 1982 · 1.5K citations · Full text

, , +16

Ketamine-Induced NMDA Receptor Hypofunction as a Model of Memory Impairment and Psychosis

John W. Newcomer · Neuropsychopharmacology · 1999 · 602 citations · Full text

, , +14

Ketamine anesthesia during the first week of life can cause long-lasting cognitive deficits in rhesus monkeys

Merle G. Paule, M. Li, Richard R. Allen et al. · Neurotoxicology and Teratology · 2011 · 568 citations · Full text

, , +12

Taming the Ketamine Tiger

Edward F. Domino, David S. Warner · Anesthesiology · 2010 · 516 citations

, , +11

Ketamine-induced Neuroapoptosis in the Fetal and Neonatal Rhesus Macaque Brain

Ansgar M. Brambrink, Alex S. Evers, Michael S. Avidan et al. · Anesthesiology · 2012 · 432 citations · Full text

, , +17

1–5 of 321

Authors

1.5K

  1. MG
    Merle G. Paule

    National Center for Toxicological Research, United States

    16 publications · 1.8K citations

    16

    h-index

  2. WS
    William Slikker

    National Center for Toxicological Research, United States

    10 publications · 1.5K citations

    10

    h-index

  3. NS
    Natalya Sadovova

    National Center for Toxicological Research, United States

    8 publications · 905 citations

    8

    h-index

  4. JP
    Joseph P. Hanig

    National Center for Toxicological Research, United States

    8 publications · 1.4K citations

    8

    h-index

  5. SF
    Syed F. Ali

    National Center for Toxicological Research, United States

    7 publications · 359 citations

    7

    h-index

1–5 of 1.5K

Institutions

534

  1. National Center for Toxicological Research

    Pine Bluff, United States

    18 h-index

    99 publications

    11K citations

  2. United States Food and Drug Administration

    Silver Spring, United States

    16 h-index

    104 publications

    7.8K citations

  3. Chinese University of Hong Kong

    Hong Kong, Hong Kong

    12 h-index

    66 publications

    3.1K citations

  4. Center for Drug Evaluation and Research

    Silver Spring, United States

    9 h-index

    20 publications

    1.9K citations

  5. National Taiwan University

    Taipei, Taiwan

    7 h-index

    23 publications

    799 citations

  6. University of Trás-os-Montes and Alto Douro

    Vila Real, Portugal

    5 h-index

    28 publications

    1.4K citations

  7. Yale University

    New Haven, United States

    5 h-index

    6 publications

    111 citations

  8. King's College London

    London, United Kingdom

    5 h-index

    8 publications

    785 citations

1–8 of 534

Venues

  1. PubMed

    Repository · 23 publications · 650 citations

    15

    h-index

  2. Anesthesia & Analgesia

    11 publications · 513 citations

    10

    h-index

  3. Anesthesiology

    9 publications · 2.9K citations

    9

    h-index

  4. Journal of Analytical Toxicology

    JAT · 6 publications · 192 citations

    7

    h-index

  5. Neuroscience Letters

    6 publications · 190 citations

    6

    h-index

1–5