Concepedia

A novel oxidative degradation pathway of indomethacin under the stressing by hydrogen peroxide

Min Li, Beth A. Conrad, Russell G. Maus, Steven M. Pitzenberger, Raju Subramanian, Xueguang Fang, Jeffery A. Kinzer, Holly J. Perpall

Tetrahedron Letters · 2005 · 16 citations · 4 references

Concepts

Life SciencesBiochemistryCellular MetabolismMetabolismRedox BiochemistryAntioxidant DefenseLipid PeroxidationOxidative Damage To BiomoleculesOxidative StressOxidative Stress MechanismsReactive Oxygen SpeciesHydrogen Peroxide TreatmentOxidative Degradation ProductsOxidative Degradation StudiesOxidative Stress In MetabolismPeroxidation Processes

References

4

Dimethyldioxirane oxidation of indole derivatives. Formation of novel indole-2,3-epoxides and a versatile synthetic route to indolinones and indolines

Xiaojun Zhang, Christopher S. Foote · Journal of the American Chemical Society · 1993 · 145 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8

The enantioselective synthesis of (-)-physostigmine via chiral sulfoxides

Joseph P. Marino, S. BOGDAN, Kiyoshi Kimura · Journal of the American Chemical Society · 1992 · 98 citations

Natural Sciences, Chemistry, Pharmacology +6

Extended-release physostigmine in Alzheimer disease: a multicenter, double-blind, 12-week study with dose enrichment. Physostigmine Study Group.

Christopher H. van Dyck · PubMed · 2000 · 30 citations

Medicine, Pharmacology, Pharmacotherapy +17

Application of chemical P-450 model systems to studies on drug metabolism. Part X. Novel hydroxylactonization of γ,δ- and β,γ- unsaturated carboxylic acids with an iron porphyrin–iodosylbenzene system

Masakatsu Komuro, Tsunehiko Higuchi, Masaaki Hirobe · Journal of the Chemical Society Perkin Transactions 1 · 1996 · 20 citations

Medicine, Biochemistry, Pharmacology +17