Regulation of osteoarthritis-associated key mediators by TNFα and IL-10: effects of IL-10 overexpression in human synovial fibroblasts and a synovial cell line

A new mathematical model for relative quantification in real-time RT-PCR

Michael W. Pfaffl · Nucleic Acids Research · 2001 · 34.9K citations · Full text

Life Sciences, Molecular Biology, Gene Expression +12

The role of cytokines in osteoarthritis pathophysiology

Julio Fernandes, Johanne Martel‐Pelletier, Jean‐Pierre Pelletier · Biorheology · 2002 · 1K citations

Dentistry, Immunology, Orthopaedic Surgery +17

Progression of Coronary Atherosclerosis Is Associated with a Common Genetic Variant of the Human Stromelysin-1 Promoter Which Results in Reduced Gene Expression

Shu Ye, Per Eriksson, Anders Hamsten et al. · Journal of Biological Chemistry · 1996 · 504 citations · Full text

Medicine, Genetics, Molecular Genetics +15

Interleukin‐6 Gene‐Deficient Mice Show Impaired Defense against Pneumococcal Pneumonia

Tom van der Poll, C V Keogh, Xavier Guirao et al. · The Journal of Infectious Diseases · 1997 · 386 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17

Synovial fibroblasts self‐direct multicellular lining architecture and synthetic function in three‐dimensional organ culture

Hans P. Kiener, Gerald F. Watts, Yajun Cui et al. · Arthritis & Rheumatism · 2010 · 129 citations

Veterinary Medicine, Cell Biology, Pathology +17