The Effect of Bergamottin on Diazepam Plasma Levels and P450 Enzymes in Beagle Dogs

Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450

M.D. Burke, S. Thompson, Clifford R. Elcombe et al. · Biochemical Pharmacology · 1985 · 1.3K citations

Medicine, Pharmacology, Drug Metabolism +8

Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression.

Kenneth S. Lown, David G. Bailey, Robert J. Fontana et al. · Journal of Clinical Investigation · 1997 · 628 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +11

Disposition of intravenous and oral cyclosporine after administration with grapefruit juice*

Murray P. Ducharme, L H Warbasse, David J. Edwards · Clinical Pharmacology & Therapeutics · 1995 · 351 citations

Pharmacy, Clinical Pharmacokinetics, Pharmacology +15

Regio- and stereoselective metabolism of two C19 steroids by five highly purified and reconstituted rat hepatic cytochrome P-450 isozymes.

Alexander W. Wood, Dene E. Ryan, Wayne Levin · Journal of Biological Chemistry · 1983 · 340 citations · Full text

Life Sciences, Biochemistry, Endocrinology +17

Inactivation of Cytochrome P450 3A4 by Bergamottin, a Component of Grapefruit Juice

Kan He, K. R. Krishna Iyer, Roger N. Hayes et al. · Chemical Research in Toxicology · 1998 · 312 citations

Medicine, Biochemistry, Pharmacology +17