Constitutive androstane receptor activation stimulates faecal bile acid excretion and reverse cholesterol transport in mice

Orphan Nuclear Receptors Constitutive Androstane Receptor and Pregnane X Receptor Share Xenobiotic and Steroid Ligands

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Medicine, Biochemistry, Pharmacology +17

Disruption of <i>Abcg5</i> and <i>Abcg8</i> in mice reveals their crucial role in biliary cholesterol secretion

Liqing Yu, Robert E. Hammer, Jia Li-Hawkins et al. · Proceedings of the National Academy of Sciences · 2002 · 715 citations

Life Sciences, Biochemistry, Molecular Biology +17

The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism

Ping Wei, Jun Zhang, Margarete Egan-Hafley et al. · Nature · 2000 · 649 citations

Medicine, Molecular Biology, Pharmacology +13

Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol

Liqing Yu, Jia Li-Hawkins, Robert E. Hammer et al. · Journal of Clinical Investigation · 2002 · 640 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

The role of reverse cholesterol transport in animals and humans and relationship to atherosclerosis

Daniel J. Rader, Eric T. Alexander, Ginny L. Weibel et al. · Journal of Lipid Research · 2008 · 603 citations · Full text

Life Sciences, Biochemistry, Cell Biology +16