Concepedia

TMEPAI inhibits TGF-β signaling by promoting lysosome degradation of TGF-β receptor and contributes to lung cancer development

Xilong Bai, Lei Jing, Yinchuan Li, Yuyin Li, Shenheng Luo, Shasha Wang, Jie Zhou, Zhe Liu, Aipo Diao

Cellular Signalling · 2014 · 32 citations · 22 references

DOI

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22

Smad7 Binds to Smurf2 to Form an E3 Ubiquitin Ligase that Targets the TGFβ Receptor for Degradation

Peter A. Kavsak, Richele K. Rasmussen, Carrie G. Causing et al. · Molecular Cell · 2000 · 1.3K citations · Full text

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Smurf1 Interacts with Transforming Growth Factor-β Type I Receptor through Smad7 and Induces Receptor Degradation

Takanori Ebisawa, Minoru Fukuchi, Gyo Murakami et al. · Journal of Biological Chemistry · 2001 · 841 citations · Full text

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NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-β (transforming growth factor-β) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-β type I receptor

Go Kuratomi, Akiyoshi Komuro, Kouichiro Goto et al. · Biochemical Journal · 2005 · 217 citations

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Negative regulation of transforming growth factor-β (TGF-β) signaling by WW domain-containing protein 1 (WWP1)

Akiyoshi Komuro, Takeshi Imamura, Masao Saitoh et al. · Oncogene · 2004 · 200 citations

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Stromal genes discriminate preinvasive from invasive disease, predict outcome, and highlight inflammatory pathways in digestive cancers

Amel Saadi, Nicholas B. Shannon, Pierre Lao-Sirieix et al. · Proceedings of the National Academy of Sciences · 2010 · 164 citations · Full text

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