Concepedia

High Performance Liquid Cbromatographic Separation of Globin Chains on a Large-Pore C<sub>4</sub>Column

Joan B. Shelton, J. Roger Shelton, W. A. Schroeder

Journal of Liquid Chromatography · 1984 · 420 citations · 7 references

DOI

Concepts

Abstract

Excellent resolution of human and baboon globin chains may be obtained by HPLC on a Vydac large-pore C4 column. The procedure is rapid and uses a gradient between aqueous trifluoroacetic acid and trifluoroacetic acid in acetonitrile. The common human γ chains are easily separable from each other as are some α- and β-chain variants from the normal chains and from each other.

References

7

The occurrence of different levels of <sup>G</sup>γ chain and of the <sup>A</sup>γ<sup>T</sup> variant of fetal hemoglobin in newborn babies from several countries

T. H. J. Huisman, A. L. Reese, Melissa Gardiner et al. · American Journal of Hematology · 1983 · 58 citations

, , +10

Detection of Hb-Papio B, a Silent Mutation of the Baboon β Chain, by High Performance Liquid Chromatography. Improved Procedures for the Separation of Globin Chains by Hplc

Joan B. Shelton, J. Roger Shelton, Werner Schroeder et al. · Hemoglobin · 1982 · 38 citations

, , +12

Further Experiments in the Separation of Globin Chains by High Performance Liquid Chromatography

Joan B. Shelton, J. Roger Shelton, W. A. Schroeder · Journal of Liquid Chromatography · 1981 · 34 citations

, , +8

Specific radioimmunochemical identification and quantitation of hemoglobins a2 and f

Fred A. Garver, Christopher S. Jones, Marilyn M. Baker et al. · American Journal of Hematology · 1976 · 34 citations

, , +16

Advances in Hemoglobin Analysis

M Brozović · Journal of Clinical Pathology · 1982 · 21 citations · Full text

, , +13