Concepedia

From COX-2 inhibitor nimesulide to potent anti-cancer agent: Synthesis, in vitro, in vivo and pharmacokinetic evaluation

Bo Zhong, Xiaohan Cai, Snigdha Chennamaneni, Xin Yi, Lili Liu, John J. Pink, Afshin Dowlati, Yan Xu, Aimin Zhou, Bin Su

European Journal of Medicinal Chemistry · 2011 · 60 citations · 41 references

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41

Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas

Charles E. Eberhart, R J Coffey, Radhika Aramandla et al. · Gastroenterology · 1994 · 2.5K citations · Full text

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Cyclooxygenase Regulates Angiogenesis Induced by Colon Cancer Cells

Masahiko Tsujii, Sunao Kawano, Shingo Tsuji et al. · Cell · 1998 · 2.3K citations · Full text

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Expression of cyclooxygenase-1 and -2 in human colorectal cancer.

Hajime Sano, Yutaka Kawahito, Ronald L. Wilder et al. · PubMed · 1995 · 1.1K citations

, , +10

Overexpression of Cyclooxygenase-2 Is Sufficient to Induce Tumorigenesis in Transgenic Mice

Catherine H. Liu, Sung-Hee Chang, Kirsi Narko et al. · Journal of Biological Chemistry · 2001 · 815 citations · Full text

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Host cyclooxygenase-2 modulates carcinoma growth

Christopher S. Williams, Masahiko Tsujii, Jeff Reese et al. · Journal of Clinical Investigation · 2000 · 677 citations · Full text

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