Journal of Plant Biotechnology · 2002 · 58 citations · 5 references
Life SciencesBiotechnologyPharmaceutical BiotechnologyGood Manufacturing PracticeMedical BiotechnologyPharmaceutical ManufacturingBiopharmaceutical ProductionCancer BiotechnologyCell CultureCell Culture TechnologyCell Line DevelopmentPlant Cell BioprocessingCell Culture BioprocessingCell Culture Process DesignCell Culture ProductionCell Factory EngineeringFda Drug RegulationFda RegulationPharmaceutical Good Manufacturing PracticePurification
Samyang Genex succeeded in commercialization of anticancer agent-paclitaxel by plant cell culture technology. The core technology of Samyang Genex relating paclitaxel production includes cell line development, cell line preservation, cell culture, scale-up technology, and purification technology. On the basis of the research, Samyang Genex built the factory operated by CGMP (current good manufacturing practice). The paclitaxel-Genexol<TEX>$^{TM}$</TEX>-is commercially available in Korea, and it will be launched to world market including USA after approval of US FDA.
5