Mass Production of Paclitaxel by Plant Cell Culture

Hyung‐Kyoon Choi, Joo-Sun Son, Gwang-Hwee Na, Seung-Suh Hong, Yeon-Seung Park, Jai-Young Song

Journal of Plant Biotechnology · 2002 · 58 citations · 5 references

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Abstract

Samyang Genex succeeded in commercialization of anticancer agent-paclitaxel by plant cell culture technology. The core technology of Samyang Genex relating paclitaxel production includes cell line development, cell line preservation, cell culture, scale-up technology, and purification technology. On the basis of the research, Samyang Genex built the factory operated by CGMP (current good manufacturing practice). The paclitaxel-Genexol<TEX>$^{TM}$</TEX>-is commercially available in Korea, and it will be launched to world market including USA after approval of US FDA.

References

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