Impairment by cyclosporin A of reperfusion-induced arrhythmias

Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins

Günter Fischer, Brigitte Wittmann‐Liebold, Kurt Lang et al. · Nature · 1989 · 1.4K citations

Life Sciences, Biochemistry, Molecular Biology +5

Inhibition by cyclosporin A of a Ca2+-dependent pore in heart mitochondria activated by inorganic phosphate and oxidative stress.

M Crompton, H Ellinger, A Costi · PubMed · 1988 · 848 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Inhibition of Ca2+-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix peptidyl-prolyl <i>cis-trans</i> isomerase and preventing it interacting with the adenine nucleotide translocase

Andrew P. Halestrap, A M Davidson · Biochemical Journal · 1990 · 746 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Cyclosporin A is a potent inhibitor of the inner membrane permeability transition in liver mitochondria

Kimberly M. Broekemeier, Mary E. Dempsey, Douglas R. Pfeiffer · Journal of Biological Chemistry · 1989 · 697 citations · Full text

Life Sciences, Biochemistry, Pharmacology +13

Demonstration of free radical generation in "stunned" myocardium of intact dogs with the use of the spin trap alpha-phenyl N-tert-butyl nitrone.

Roberto Bolli, Brijeshkumar S. Patel, Mohamed O. Jeroudi et al. · Journal of Clinical Investigation · 1988 · 686 citations · Full text

Life Sciences, Biochemistry, Cardiology +13