Concepedia

Overexpression of glucosylceramide synthase in associated with multidrug resistance of leukemia cells

Ping Xie, Yunfen Shen, Yuanping Shi, Shu-Mei Ge, Zhong-Hua Gu, Jue Wang, Hui‐Jun Mu, Bin Zhang, Weizhen Qiao, Xie Ke-ming

Leukemia Research · 2007 · 57 citations · 24 references

DOI

Concepts

References

24

Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine.

Kazumitsu Ueda, Carol Cardarelli, Michael M. Gottesman et al. · Proceedings of the National Academy of Sciences · 1987 · 1.1K citations · Full text

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Ceramide activates heterotrimeric protein phosphatase 2A

Rick T. Dobrowsky, Craig Kamibayashi, Marc C. Mumby et al. · Journal of Biological Chemistry · 1993 · 663 citations · Full text

, , +15

Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs.

Caroline E. Grant, Gunnar Valdimarsson, David R. Hipfner et al. · PubMed · 1994 · 635 citations

, , +16

Accumulation of Glucosylceramides in Multidrug-resistant Cancer Cells

Yaakov Lavie, Hui-Ting Cao, Stuart L. Bursten et al. · Journal of Biological Chemistry · 1996 · 342 citations · Full text

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Phosphorylation of Raf by ceramide-activated protein kinase

Bei Yao, Yuhua Zhang, Sylvie Delikat et al. · Nature · 1995 · 330 citations

, , +10