Sex- and age-dependent effects of Gpr30 genetic deletion on the metabolic and cardiovascular profiles of diet-induced obese mice

A Transmembrane Intracellular Estrogen Receptor Mediates Rapid Cell Signaling

Chetana M. Revankar, Daniel F. Cimino, Larry A. Sklar et al. · Science · 2005 · 2.3K citations

Life Sciences, Biochemistry, Cell Biology +10

Estrogen-Induced Activation of Erk-1 and Erk-2 Requires the G Protein-Coupled Receptor Homolog, GPR30, and Occurs via Trans-Activation of the Epidermal Growth Factor Receptor through Release of HB-EGF

Edward J. Filardo, Jeffrey A. Quinn, Kirby I. Bland et al. · Molecular Endocrinology · 2000 · 1.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Estrogen Action Via the G Protein-Coupled Receptor, GPR30: Stimulation of Adenylyl Cyclase and cAMP-Mediated Attenuation of the Epidermal Growth Factor Receptor-to-MAPK Signaling Axis

Edward J. Filardo, Jeffrey A. Quinn, A. Raymond Frackelton et al. · Molecular Endocrinology · 2002 · 854 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Virtual and biomolecular screening converge on a selective agonist for GPR30

Cristian Bologa, Chetana M. Revankar, Susan Young et al. · Nature Chemical Biology · 2006 · 814 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Identification of a Gene (GPR30) with Homology to the G-Protein-Coupled Receptor Superfamily Associated with Estrogen Receptor Expression in Breast Cancer

Charles Carmeci, Devon A. Thompson, Huijun Z. Ring et al. · Genomics · 1997 · 578 citations

Life Sciences, Molecular Biology, Oncology +13