Concepedia

Models of hepatic elimination: Comparison of stochastic models to describe residence time distributions and to predict the influence of drug distribution, enzyme heterogeneity, and systemic recycling on hepatic elimination

Michael S. Roberts, J. D. Donaldson, Malcolm Rowland

Journal of Pharmacokinetics and Biopharmaceutics · 1988 · 110 citations · 47 references

References

47

Chemical Reaction Engineering

Octave Levenspiel · Industrial & Engineering Chemistry Research · 1999 · 10K citations

Engineering, Chemical Engineering, Chemistry +6

Clinical pharmacokinetics; concepts and applications

General Pharmacology The Vascular System · 1989 · 2.2K citations

Pharmacy, Clinical Pharmacokinetics, Pharmacokinetics +12

Lectu re Notes in Biomathematics

Simon A. Levin · 1983 · 1.6K citations

Engineering, Bioengineering, Biomechanics +1

Hepatic clearance of drugs. I. Theoretical considerations of a “well-stirred” model and a “parallel tube” model. Influence of hepatic blood flow, plasma and blood cell binding, and the hepatocellular enzymatic activity on hepatic drug clearance

K. Sandy Pang, Malcolm Rowland · Journal of Pharmacokinetics and Biopharmaceutics · 1977 · 798 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Clearance concepts in pharmacokinetics

Malcolm Rowland, Leslie Z. Benet, Garry G. Graham · Journal of Pharmacokinetics and Biopharmaceutics · 1973 · 764 citations

Pharmacy, Pharmacokinetics, Pharmacology +10