REPEAT BIOPSY STRATEGY IN PATIENTS WITH ATYPICAL SMALL ACINAR PROLIFERATION OR HIGH GRADE PROSTATIC INTRAEPITHELIAL NEOPLASIA ON INITIAL PROSTATE NEEDLE BIOPSY

Abstract

Patients with isolated high grade prostatic intraepithelial neoplasia and/or atypical small acinar proliferation on prostate biopsy are at 47% risk for cancer on repeat biopsy. The optimal repeat biopsy strategy in this setting should include bilateral biopsies of the standard sextant locations. We also strongly recommend that transition zone sampling should be considered.