Prostatic Intraepithelial Neoplasia is Risk Factor for Adenocarcinoma: Predictive Accuracy in Needle Biopsies

Abstract

These results indicate that the presence of high grade prostatic intraepithelial neoplasia on needle biopsy is strongly predictive of carcinoma. Prostatic intraepithelial neoplasia should be reported in needle biopsies and biopsy repeated. These finding support the hypothesis that prostatic intraepithelial neoplasia is a precursor of prostate cancer.