HSP70 Enhances Macrophage Phagocytosis by Interaction With Lipid Raft-Associated TLR-7 and Upregulating p38 MAPK and PI3K Pathways

Recognition of single-stranded RNA viruses by Toll-like receptor 7

Jennifer M. Lund, Lena Alexopoulou, Ayuko Sato et al. · Proceedings of the National Academy of Sciences · 2004 · 1.8K citations · Full text

Life Sciences, Immunology, Molecular Biology +17

HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine

Alexzander Asea, Stine‐Kathrein Kraeft, Evelyn A. Kurt‐Jones et al. · Nature Medicine · 2000 · 1.6K citations

Life Sciences, Cell Biology, Immunology +14

Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-κB pathway

Sreyashi Basu, Robert Binder, Ryuichiro Suto et al. · International Immunology · 2000 · 1.3K citations · Full text

Life Sciences, Immunology, Molecular Biology +17

CD91 Is a Common Receptor for Heat Shock Proteins gp96, hsp90, hsp70, and Calreticulin

Sreyashi Basu, Robert Binder, Thirumalai R. Ramalingam et al. · Immunity · 2001 · 1.1K citations · Full text

Life Sciences, Immunology, Molecular Biology +6

Analysis of gene function in somatic mammalian cells using small interfering RNAs

Sayda M. Elbashir · Methods · 2002 · 1.1K citations · Full text

Life Sciences, Genetics, Molecular Biology +14