Accuracy of calculated pH-dependent aqueous drug solubility

A Common Mechanism Underlying Promiscuous Inhibitors from Virtual and High-Throughput Screening

Susan L. McGovern, Emilia Caselli, Nikolaus Grigorieff et al. · Journal of Medicinal Chemistry · 2002 · 1K citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Polar Molecular Surface Properties Predict the Intestinal Absorption of Drugs in Humans

Katrin Palm, Patric Stenberg, Kristina Luthman et al. · Pharmaceutical Research · 1997 · 751 citations

Pharmacy, Pharmacokinetics, Pharmacology +14

Mechanism of protein salting in and salting out by divalent cation salts: balance between hydration and salt binding

Tsutomu Arakawa, Serge N. Timasheff · Biochemistry · 1984 · 666 citations

Natural Sciences, Biochemistry, Chemistry +13

Linear free-energy relationship between partition coefficients and the aqueous solubility of organic liquids

Corwin Hansch, John E. Quinlan, Gary L. Lawrence · The Journal of Organic Chemistry · 1968 · 454 citations

Natural Sciences, Chemistry, Organic Chemistry +12

Prediction of drug solubility from Monte Carlo simulations

William L. Jorgensen, Erin M. Duffy · Bioorganic & Medicinal Chemistry Letters · 2000 · 368 citations

Pharmacy, Pharmaceutics, Pharmacokinetics +12