Prolonged in vivo tumour retention of a human diabody targeting the extracellular domain of human HER2/neu

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/<i>neu</i>Oncogene

Dennis J. Slamon, Gary M. Clark, Steven Wong et al. · Science · 1987 · 11.7K citations

Medicine, Genetics, Oncology +14

By-passing immunization

James D. Marks, Hennie R. Hoogenboom, Timothy P. Bonnert et al. · Journal of Molecular Biology · 1991 · 1.6K citations

Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli.

James S. Huston, Dennis J. Levinson, M Mudgett-Hunter et al. · Proceedings of the National Academy of Sciences · 1988 · 1.6K citations · Full text

Engineering, Biochemistry, Molecular Biology +17

Single-Chain Antigen-Binding Proteins

Robert E. Bird, Karl D. Hardman, James W. Jacobson et al. · Science · 1988 · 1.5K citations

Pharmacy, Biochemistry, Molecular Biology +13

Kinetic analysis of monoclonal antibody-antigen interactions with a new biosensor based analytical system

Robert Karlsson, Anne Michaelsson, Lars Mattsson · Journal of Immunological Methods · 1991 · 1.1K citations

Pharmacy, Biochemistry, Immunology +17