Concepedia

Myoclonic seizures following chlorambucil overdose

Thomas N. Byrne, Thomas A. E. Moseley, Michael A. Finer

Annals of Neurology · 1981 · 29 citations · 8 references

DOI

Concepts

Abstract

A 3 1/2-year-old child developed myoclonic seizures following a chlorambucil overdose. Serial electroencephalograms showed paroxysmal discharges that continued several days beyond clinical seizure activity. The use of the electroencephalogram when chlorambucil toxicity is suspected is discussed.

References

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Long-Term Evaluation of Chlorambucil plus Prednisone in the Idiopathic Nephrotic Syndrome of Childhood

Sudesh P. Makker, Julie R. Ingelfinger, Warren E. Grupe · New England Journal of Medicine · 1980 · 80 citations

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Inhibition by Arousal of Epilepsy Induced by Chlorambucil in Rats

John P. J. Pinel, Stephan L. Chorover · Nature · 1972 · 48 citations

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Seizures: A significant side effect of chlorambucil therapy in children

Susan A. Williams, Sudesh P. Makker, Warren E. Grupe · The Journal of Pediatrics · 1978 · 42 citations

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Chlorambucil Toxicity and EEG “Centrencephalic” Patterns

S.N. Pradhan, Cosimo Ajmone Marsan · Epilepsia · 1963 · 32 citations

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