Liquid chromatographic method for the determination of plasma itraconazole and its hydroxy metabolite in pharmacokinetic/bioavailability studies

Pharmacokinetics of itraconazole following oral administration to normal volunteers

T C Hardin, John R. Graybill, Richard J. Fetchick et al. · Antimicrobial Agents and Chemotherapy · 1988 · 298 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16

Comparison of itraconazole and fluconazole in treatment of cryptococcal meningitis and candida pyelonephritis in rabbits

John R. Perfect, D V Savani, D T Durack · Antimicrobial Agents and Chemotherapy · 1986 · 185 citations

Medicine, Infectious Diseases, Pharmacology +17

The effects of food and dose on the oral systemic availability of itraconazole in healthy subjects

A. Van Peer, R. Woestenborghs, J. Heykants et al. · European Journal of Clinical Pharmacology · 1989 · 176 citations

Pharmacy, Pharmacology, Bioavailability +6

Penetration of imidazoles and triazoles into cerebrospinal fluid of rabbits

John R. Perfect, David T. Durack · Journal of Antimicrobial Chemotherapy · 1985 · 107 citations

Medicine, Pharmacokinetics, Pharmacology +14

Determination of itraconazole in plasma and animal tissues by high-performance liquid chromatography

Robert Woestenborghs, W. Lorreyne, J. Heykants · Journal of Chromatography B Biomedical Sciences and Applications · 1987 · 98 citations

Pharmacy, Pharmacokinetics, Pharmacology +13