Analysis of crude heparin by 1H NMR, capillary electrophoresis, and strong-anion-exchange-HPLC for contamination by over sulfated chondroitin sulfate

Contaminated Heparin Associated with Adverse Clinical Events and Activation of the Contact System

Takashi Kishimoto, Karthik Viswanathan, Tanmoy Ganguly et al. · New England Journal of Medicine · 2008 · 613 citations · Full text

Oversulfated chondroitin sulfate is a contaminant in heparin associated with adverse clinical events

Marco Guerrini, Daniela Beccati, Zachary Shriver et al. · Nature Biotechnology · 2008 · 612 citations

Chondroitin Sulfate, Adverse Clinical Events, Pharmacology +4

Conformational changes and anticoagulant activity of chondroitin sulfate following its O-sulfonation

Tomohiro Maruyama, Toshihiko Toida, Toshio Imanari et al. · Carbohydrate Research · 1998 · 153 citations

Chondroitin Sulfate, Biochemistry, Medicine +6

Isolation and characterization of heparan sulfate from crude porcine intestinal mucosal peptidoglycan heparin

Charles C. Griffin, Robert J. Linhardt, Cornelius L. Van Gorp et al. · Carbohydrate Research · 1995 · 118 citations

Biochemistry, Medicine, Glycobiology +2

Quality assessment of unfractionated heparin using 1H nuclear magnetic resonance spectroscopy

Tanja Beyer, Bernd Diehl, Gabriele Randel et al. · Journal of Pharmaceutical and Biomedical Analysis · 2008 · 90 citations

Unfractionated Heparin, Bioanalysis, Resonance +7