Peyer's Patch Dendritic Cells Sample Antigens by Extending Dendrites Through M Cell-Specific Transcellular Pores

Hugues Lelouard, Mathieu Fallet, Béatrice de Bovis, Stéphane Méresse, Jean‐Pierre Gorvel

Gastroenterology · 2011 · 233 citations · 34 references

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Abstract

We describe an antigen sampling mechanism that occurs in PPs and involves cooperation between M cells of the follicle-associated epithelium and DCs of the subepithelial dome. This process might be developed to target vaccines to the mucosa.

References

34